Solgar Curcumin Redox 30 softgel pearls

Turmeric is a plant with a rather imposing underground rhizome from which a yellow-orange powder used as a spice or food coloring is obtained. The main curcuminoids present in the rhizome are curcumin (which represents 70-75% of the total curcuminoids), demethoxycurcumin (15-20%) and bisdemethoxycurcumin (approximately 3%).

Turmeric is traditionally used to support digestive and liver function by promoting the functionality of the digestive system. Its action in supporting joint function and its antioxidant action have also been demonstrated.

Curcumin and other curcuminoids have various beneficial properties. According to a brief description reported by the National Cancer Institute (NCI), curcumin blocks the formation of reactive oxygen species, inhibits the enzyme cyclooxygenase (COX) and other enzymes involved in inflammatory mechanisms and inhibits the transduction of cellular signals thanks to different mechanisms including inhibition of protein kinase C. These activities could explain the effects of inhibition of cell proliferation and suppression of chemically induced carcinogenesis observed in animal models. In this regard, at the moment (December 2015), there are 6 clinical studies that are verifying the effects of curcumin in these areas but whose discussion goes beyond the scope of this technical sheet.

Curcumin, being a lipophilic molecule, is subject to this slow and variable absorption mechanism and characterized by a rapid degradation metabolism. When you want to formulate a food supplement containing Curcumin the main challenge is bioavailability. In recent years, various methods and strategies have been developed to improve the absorption and permanence of Curcumin and today Solgar launches a formulation with Curcumin with an exceptional and unique transport system which significantly improves its bioavailability.

Curcumin Redox in fact uses a unique, exclusive technology whose patent is being registered, thanks to which curcumin is more easily assimilated by the body because it mimics the natural digestive processes which allow the absorption of lipophilic compounds through a process of micellization. The micellar matrix is stable to gastric acidity and the curcumin is released directly into the intestinal wall for maximum absorption.

This innovative formulation was the subject of a clinical study (Schiborr C et al. The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes. Mol Nutr Food Res. 2014 Mar;58(3) :516-27) thanks to which there is an increased bioavailability of 185 times compared to curcumin in native form. Indeed, curcumin in micelles is absorbed 6.8 times faster than curcumin in native form.

More recent studies indicate that curcumin, since it is able to cross the blood-brain barrier, could possess neuroprotective properties and support normal cognitive activity, suggesting its use as an integrative support where highly bioavailable formulations would find a logical rationale for use.

Ingredients
Full Spectrum Curcumin 800 mg (standardized extract of Curcuma longa L. rhizome) of which:
- Total curcuminoids 48 mg
- Curcumin 40 mg
- Emulsifier: Polysorbate 80 766 mg
- Edible gelatine 241 mg
- Humidifier: Vegetable glycerol 135 mg

sugar, salt, starch, gluten, wheat, yeast, soy, milk derivatives, colours, flavors and artificial sweeteners are not used in the preparation of the product.

Instructions for use
Swallow 1 pearl a day, with water, preferably with a meal.

Precautions for use
Not recommended during pregnancy and breastfeeding.
In the presence of blockage of the passages under medical supervision.